yourfanat wrote: I am using another tool for Oracle developers - dbForge Studio for Oracle. This IDE has lots of usefull features, among them: oracle designer, code competion and formatter, query builder, debugger, profiler, erxport/import, reports and many others. The latest version supports Oracle 12C. More information here.

2008 West
Data Direct
SOA, WOA and Cloud Computing: The New Frontier for Data Services
Red Hat
The Opening of Virtualization
User Environment Management – The Third Layer of the Desktop
Cloud Computing for Business Agility
CMIS: A Multi-Vendor Proposal for a Service-Based Content Management Interoperability Standard
Freedom OSS
Practical SOA” Max Yankelevich
Architecting an Enterprise Service Router (ESR) – A Cost-Effective Way to Scale SOA Across the Enterprise
Return on Assests: Bringing Visibility to your SOA Strategy
Managing Hybrid Endpoint Environments
Game-Changing Technology for Enterprise Clouds and Applications
Click For 2008 West
Event Webcasts

2008 West
Get ‘Rich’ Quick: Rapid Prototyping for RIA with ZERO Server Code
Keynote Systems
Designing for and Managing Performance in the New Frontier of Rich Internet Applications
How Can AJAX Improve Homeland Security?
Beyond Widgets: What a RIA Platform Should Offer
REAs: Rich Enterprise Applications
Click For 2008 Event Webcasts
Today's Top SOA Links

Microbiotix Announces Exclusive Worldwide Licensing Agreement for HCV NS5B Non-Nucleoside Polymerase Inhibitors

WORCESTER, Mass., Jan. 2, 2013 /PRNewswire/ -- Microbiotix, Inc., a privately-held, clinical stage biopharmaceutical company engaged in the discovery and development of novel small molecule anti-infective drugs, announced today that it has entered into an exclusive licensing agreement with Merck, known as MSD outside the United States and Canada.

As part of this agreement, Microbiotix gains worldwide rights to develop, manufacture and commercialize MBX-700 and MBX-701 (formerly SCH 900942 and SCH 900188), two non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase. MBX-700 is in Phase I clinical testing and MBX-701 is currently in preclinical development. Merck is eligible for milestone payments during development stages of the candidates, and for royalty payments from any resulting products. Specific terms of the agreement were not disclosed.

MBX-700 and MBX-701 are designed to inhibit the replication of the hepatitis C virus by acting on the NS5B polymerase, a clinically validated target that is essential for viral genome replication. In vitro studies have shown MBX-700 to be among the most potent HCV NS5B polymerase inhibitors.

"This agreement with Merck significantly strengthens our antiviral portfolio," said Terry L. Bowlin, PhD, President & CEO, Microbiotix. "We believe MBX-700 and MBX-701 have great potential as potent ingredients in future combination drug therapy. Our preclinical studies have demonstrated high potency while the Phase I clinical study has shown MBX-700 to be safe and well-tolerated."

"Merck remains committed to the development of therapies for the treatment of hepatitis C," said Eliav Barr, vice president, Infectious Diseases Project Leadership and Management, Merck Research Laboratories. "Our discovery programs have identified a number of well-characterized candidates targeting hepatitis C. Outlicensing deals, such as this one, allow Merck to harness potential value from these assets while ensuring they are developed to their full potential."

About Hepatitis C
Hepatitis C, which primarily affects the liver, is an infectious disease caused by the hepatitis C virus (HCV). HCV infection becomes chronic in 75%-85% of cases and, if left untreated, can lead to chronic liver disease, liver cancer or death. It is estimated that 170 million people worldwide are chronically infected with the hepatitis C virus.

About Microbiotix, Inc.
Microbiotix, Inc., located in Worcester, MA, is a biopharmaceutical company focused on the discovery and development of proprietary small molecule drugs that target serious infectious diseases. The Company's lead therapeutic compound, MBX-700, is a non-nucleoside inhibitor of the HCV NS5B polymerase. In vitro studies have shown MBX-700 to be among the most potent HCV polymerase inhibitors. MBX-700 is in Phase I clinical testing. MBX-701, a non-nucleoside inhibitor also targeting the HCV NS5B polymerase, is in preclinical development. The Company's second clinical compound, MBX-400, a novel agent for the treatment of human cytomegalovirus, is also in Phase I clinical testing.

SOURCE Microbiotix, Inc.

About PR Newswire
Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Web 2.0 Latest News
Today, organizations have so much data at their disposal. This data includes company, customer, product, employee, and more… much more. The problem is that without the proper tools, mid-market companies often struggle with turning this information into meaningful and actionable insight...
The annual holiday shopping season, which started on Thanksgiving weekend and runs through the end of December, is undoubtedly the most crucial time of the year for many eCommerce websites, with sales from this period having a dramatic effect on the year-end bottom line. Web performan...
Unicorn is a term in the investment industry, and in particular the venture capital industry, which denotes a start-up company whose valuation has exceeded (the somewhat arbitrary) $1 billion. The term has been popularized by Aileen Lee of Cowboy Ventures. Fortune magazine counted over...
Intuit uses deep-data analytics to gain a 360-degree view of its TurboTax application's users’ behavior and preferences for rapid applications improvements. The next BriefingsDirect big-data innovation case study highlights how Intuit uses deep-data analytics to gain a 360-degree view...
Here’s the thing: as sure as we’ll have another record-setting year for NFL streaming, you can also be sure that apps will fail and streaming services will go down. Whether you are dabbling in streaming or diving in whole-hog, you need to know what to do to give your users the most rel...
Subscribe to the World's Most Powerful Newsletters
Subscribe to Our Rss Feeds & Get Your SYS-CON News Live!
Click to Add our RSS Feeds to the Service of Your Choice:
Google Reader or Homepage Add to My Yahoo! Subscribe with Bloglines Subscribe in NewsGator Online
myFeedster Add to My AOL Subscribe in Rojo Add 'Hugg' to Newsburst from CNET Kinja Digest View Additional SYS-CON Feeds
Publish Your Article! Please send it to editorial(at)!

Advertise on this site! Contact advertising(at)! 201 802-3021

SYS-CON Featured Whitepapers