yourfanat wrote: I am using another tool for Oracle developers - dbForge Studio for Oracle. This IDE has lots of usefull features, among them: oracle designer, code competion and formatter, query builder, debugger, profiler, erxport/import, reports and many others. The latest version supports Oracle 12C. More information here.

2008 West
Data Direct
SOA, WOA and Cloud Computing: The New Frontier for Data Services
Red Hat
The Opening of Virtualization
User Environment Management – The Third Layer of the Desktop
Cloud Computing for Business Agility
CMIS: A Multi-Vendor Proposal for a Service-Based Content Management Interoperability Standard
Freedom OSS
Practical SOA” Max Yankelevich
Architecting an Enterprise Service Router (ESR) – A Cost-Effective Way to Scale SOA Across the Enterprise
Return on Assests: Bringing Visibility to your SOA Strategy
Managing Hybrid Endpoint Environments
Game-Changing Technology for Enterprise Clouds and Applications
Click For 2008 West
Event Webcasts

2008 West
Get ‘Rich’ Quick: Rapid Prototyping for RIA with ZERO Server Code
Keynote Systems
Designing for and Managing Performance in the New Frontier of Rich Internet Applications
How Can AJAX Improve Homeland Security?
Beyond Widgets: What a RIA Platform Should Offer
REAs: Rich Enterprise Applications
Click For 2008 Event Webcasts
Today's Top SOA Links

The ALS Association Announces New Research Awards to Focus on Therapies for Lou Gehrig's Disease

WASHINGTON, Nov. 30, 2012 /PRNewswire-USNewswire/ -- The ALS Association will add ten awards totaling $2.9 million to its Translational Research Advancing Therapies for ALS (TREAT ALS™) portfolio, funding two clinical management grants, three drug discovery contracts, two clinical pilot studies and three biomarker studies—all focused on finding improved treatments for people with amyotrophic lateral sclerosis (ALS), otherwise known as Lou Gehrig's disease. The ALS Association's TREAT ALS ™ portfolio presently has 80 active research projects with a total award value of $12 million.

Due to the deadly and often rapid nature of ALS, a need exists for treatments and a cure for this disease as there is only one drug approved by the U.S. Food and Drug Administration (FDA) that modestly extends survival. ALS is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Eventually, people with ALS lose the ability to initiate and control muscle movement, which often leads to total paralysis and death within two to five years of diagnosis. For unknown reasons, veterans are twice as likely to develop ALS as the general population.

The two clinical management grants, which intend to expand access to care for people with ALS will analyze remote forms of treatments. Edward Kasarskis, M.D., and Richard Kryscio, Ph.D., with the University of Kentucky Research Foundation in Lexington, Ky. will devise and monitor a virtual ALS center that could provide people with the disease with multidisciplinary care remotely in their homes. James Berry, M.D., and Merit Cudkowicz, M.D., with the Massachusetts General Hospital in Boston, Mass. have devised a "telehealth" initiative to assess a videoconferencing program that offers home health providers tools to provide care to people with ALS in homes.

The three drug discovery contracts awarded by The ALS Association will support the pre-clinical assessment of therapeutics for the disease, and researchers expect they will lead to the progress of new therapies for ALS. Researchers leading these projects include: Oleg Butovsky, Ph.D., with Brigham and Women's Hospital in Boston, Mass.; Steven Burden, Ph.D., with Skirball Institute, New York University Medical School, in New York; and Rita Sattler, Ph.D., and Jeffrey Rothstein, M.D., Ph.D., at Johns Hopkins University School of Medicine in Baltimore, Maryland.

In addition to the clinical management grants and drug discovery contracts, The ALS Association is supporting two novel clinical pilot studies involving people with ALS with the Northeast ALS Consortium (NEALS) Clinical Trials Network. Jonathan Glass, M.D., and Christina Fournier, M.D., with Emory University in Atlanta, along with Merit Cudkowicz, M.D., and James Berry M.D., in Boston, Mass. will work together to determine whether they can identify a subset of people with ALS that respond to immune suppressing medication. Additionally, Jeremy Shefner, M.D., Ph.D., with SUNY Upstate Medical University in Syracuse, N.Y. will test Cogane™, a small, non-peptide agent that can penetrate the brain and spinal cord, which has been shown to improve the number of functional motor units and increased the life span in mouse models of ALS.

The ALS Association will also fund three biomarker studies, which could accelerate diagnosis of the disease and hasten clinical trials. Two of the three studies were supported by EMD/ALS Biomarker Research Fund through the Keith Worthington Chapter of The ALS Association.  Researchers include Michael Benatar, M.D., and Joanne Wuu, both with the University of Miami Miller School of Medicine in Miami, Fla., who will look for predictive biomarkers in patients with a genetic form of the disease before they develop symptoms. Patricia Anders, MHG, Boston, Mass. will develop a strength testing device that may more accurately measure response to therapy.  And finally, Lyl Ostrowe, M.D., Ph.D.; Dean Wong, M.D., Ph.D. and Jeffrey Rothstein, M.D., Ph.D., all with Johns Hopkins University, will assess whether a PET imaging marker can accurately distinguish between people with ALS and healthy subjects.

To view a full listing of these awards, please visit

About The ALS Association

The ALS Association is the only national non-profit organization fighting Lou Gehrig's Disease on every front.  By leading the way in global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships, The Association builds hope and enhances quality of life while aggressively searching for new treatments and a cure.  For more information about The ALS Association, visit our website at

SOURCE The ALS Association

About PR Newswire
Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Web 2.0 Latest News
DevOps Summit at Cloud Expo 2014 Silicon Valley was a terrific event for us. The Qubell booth was crowded on all three days. We ran demos every 30 minutes with folks lining up to get a seat and usually standing around. It was great to meet and talk to over 500 people! My keynote was we...
Are you a winner? Are you someone who always gets what they want? Are you one of those people who do what they set their eyes on no matter what the circumstances? If you answered yes to all of these questions then you are among the highly successful people in the world that have a prov...
The iPad sales are down, but it is now possible to run most business apps on the iPad with the Citrix X1 Mouse. Can this make the iPad more relevant for business? Despite the mostly positive financial news from Apple, the one weakness that gets a lot of press is the decrease in iPad s...
Forbes called 2015, the Year of the Mobile Beacon. AdWeek talks about how beacons are already influencing the way we network, get drunk, vacation, shop, and even how we buy sausage. Ten experts at Marketing Land predicted that this year the whole world of mobile marketing will become ...
Ever wondered if your marketing efforts for an in-store sale or event are impacting, or even reaching, your customers? Foot traffic is a great indicator of marketing effectiveness. By comparing foot traffic before, during and after sale promotions you’re able to identify if any increas...
Subscribe to the World's Most Powerful Newsletters
Subscribe to Our Rss Feeds & Get Your SYS-CON News Live!
Click to Add our RSS Feeds to the Service of Your Choice:
Google Reader or Homepage Add to My Yahoo! Subscribe with Bloglines Subscribe in NewsGator Online
myFeedster Add to My AOL Subscribe in Rojo Add 'Hugg' to Newsburst from CNET Kinja Digest View Additional SYS-CON Feeds
Publish Your Article! Please send it to editorial(at)!

Advertise on this site! Contact advertising(at)! 201 802-3021

SYS-CON Featured Whitepapers