yourfanat wrote: I am using another tool for Oracle developers - dbForge Studio for Oracle. This IDE has lots of usefull features, among them: oracle designer, code competion and formatter, query builder, debugger, profiler, erxport/import, reports and many others. The latest version supports Oracle 12C. More information here.

2008 West
Data Direct
SOA, WOA and Cloud Computing: The New Frontier for Data Services
Red Hat
The Opening of Virtualization
User Environment Management – The Third Layer of the Desktop
Cloud Computing for Business Agility
CMIS: A Multi-Vendor Proposal for a Service-Based Content Management Interoperability Standard
Freedom OSS
Practical SOA” Max Yankelevich
Architecting an Enterprise Service Router (ESR) – A Cost-Effective Way to Scale SOA Across the Enterprise
Return on Assests: Bringing Visibility to your SOA Strategy
Managing Hybrid Endpoint Environments
Game-Changing Technology for Enterprise Clouds and Applications
Click For 2008 West
Event Webcasts

2008 West
Get ‘Rich’ Quick: Rapid Prototyping for RIA with ZERO Server Code
Keynote Systems
Designing for and Managing Performance in the New Frontier of Rich Internet Applications
How Can AJAX Improve Homeland Security?
Beyond Widgets: What a RIA Platform Should Offer
REAs: Rich Enterprise Applications
Click For 2008 Event Webcasts
Today's Top SOA Links

The Connection between Fatty Liver Disease and the Increase in the Rate of Liver Cancer
Presented: Sunday, November 11, 4:45 pm, Liver Meeting®, Hynes Convention Center

BOSTON, Nov. 10, 2012 /PRNewswire/ -- Researchers at the University of Missouri determined that cirrhosis was not present in more than one-third of patients who had nonalcoholic fatty liver disease (NAFLD) that led to hepatocellular carcinoma (HCC). The records of 17,785 Medicare patients who had HCC were studied, and it was determined that 16 percent of those patients had NAFLD and no other way of developing cancer. About 64 percent of those patients had nonalcoholic steatohepatitis (NASH) that progressed to cirrhosis. A very surprising 36 percent of patients who developed HCC from fatty liver disease had no evidence of cirrhosis.

According to the National Institute of Diabetes and Digestive and Kidney Diseases, approximately 5 percent of the US population has nonalcoholic steatohepatitis (NASH), which is a type of NAFLD that can lead to cirrhosis and liver cancer. Cirrhosis is damage to the liver tissue that leads to loss of liver function. Many more Americans -- between 10 and 20 percent more -- have NAFLD, which is the mere presence of fat in the liver, rather than NASH. Approximately 70 percent of those diagnosed with NASH are obese.

HCC is one of the few cancers growing in incidence. Fatty liver disease is the third most common risk factor of HCC in the United States. Determining that a great number of the population can have the more benign form of liver disease without any cirrhosis present yet still develop what is considered one of the deadliest cancers in the US should be of grave concern to a country that is facing an obesity epidemic.

The researchers also indicated that in recent years the incidence of NAFLD HCC without cirrhosis is increasing more rapidly than any other cause, which could be attributed to the obesity epidemic.

Dr. Jamal Ibdah spoke to the obesity epidemic and the rise in the rate of HCC, "According to current literature, we do not have a good explanation for the recent increase in the incidence of HCC in the US population. The incidence of HCC from hepatitis or alcohol is more or less stable in the last decade. Our findings provide a potential explanation to the recent increase in the incidence of HCC, which coincides with the obesity epidemic."

Researchers did note, however, the better survival rate for patients with NAFLD HCC without cirrhosis.  

"Our data suggest unique underlying pathophysiology for development of HCC in non-cirrhotic NAFLD and further studies are warranted in this regard," said Dr. Ibdah. "This may lead to the discovery of new pathways that may become potential targets for new treatments for liver cancer."

The results of this study have important implications for physicians treating patients with NAFLD. "Physicians should be more aware that patients can develop primary liver cancer from NAFLD without cirrhosis. Surveillance for cancer is typically performed in the setting of cirrhosis. Thus, patients with NAFLD and without cirrhosis may need to be considered for periodic surveillance for HCC," said Dr. Ibdah.

Abstract title: 
Nonalcoholic fatty liver disease without cirrhosis is an emergent and independent risk factor of hepatocellular carcinoma: A population based study

AASLD is the leading medical organization for advancing the science and practice of hepatology. Founded by physicians in 1950, AASLD's vision is to prevent and cure liver diseases. This year's Liver Meeting®, held in Boston, Massachusetts November 9 – 13, will bring together more than 9,000 researchers from 55 countries.

A pressroom will be available from November 10 at the annual meeting. For copies of abstracts and press releases, or to arrange researcher interviews, contact Gregory Bologna at 703-299-9766.

Press releases and all abstracts are available online at

Media Contact: Gregory Bologna
Press Room: November 10 – 13, 2012
Hynes Convention Center, Boston, MA
Telephone: 617-954-2624

Researcher: Jamal Ibdah, MD, PhD
Phone: 573-882-7349

This release was issued through The Xpress Press News Service, merging e-mail and satellite distribution technologies to reach business analysts and media outlets worldwide. For more information, visit


SOURCE American Association for the Study of Liver Diseases (AASLD)

About PR Newswire
Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Web 2.0 Latest News
Recently announced Azure Data Lake addresses the big data 3V challenges; volume, velocity and variety. It is one more storage feature in addition to blobs and SQL Azure database. Azure Data Lake (should have been Azure Data Ocean IMHO) is really omnipotent. Just look at the key capabi...
Azure IoT Suite became Generally Available starting September 29. This suite consist of technologies to monitor and manage devices that come under Internet of Things. Microsoft according to Scott Guthrie provides advanced capabilites like stream processing and predictive analytics. En...
Scott Guthrie's keynote presentation "Journey to the intelligent cloud" is a must view video. This is from AzureCon 2015, September 29, 2015 I have reproduced some screen shots in case you are unable to view this long video for one reason or another. One of the highlights is 3 data...
Are you a winner? Are you someone who always gets what they want? Are you one of those people who do what they set their eyes on no matter what the circumstances? If you answered yes to all of these questions then you are among the highly successful people in the world that have a prov...
DevOps Summit at Cloud Expo 2014 Silicon Valley was a terrific event for us. The Qubell booth was crowded on all three days. We ran demos every 30 minutes with folks lining up to get a seat and usually standing around. It was great to meet and talk to over 500 people! My keynote was we...
Subscribe to the World's Most Powerful Newsletters
Subscribe to Our Rss Feeds & Get Your SYS-CON News Live!
Click to Add our RSS Feeds to the Service of Your Choice:
Google Reader or Homepage Add to My Yahoo! Subscribe with Bloglines Subscribe in NewsGator Online
myFeedster Add to My AOL Subscribe in Rojo Add 'Hugg' to Newsburst from CNET Kinja Digest View Additional SYS-CON Feeds
Publish Your Article! Please send it to editorial(at)!

Advertise on this site! Contact advertising(at)! 201 802-3021

SYS-CON Featured Whitepapers